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Exploring PhoSfomes: from basic biology to drug discovery

Exploring PhoSfomes: from basic biology to drug discovery

Head of Biochemistry and Systems Biology Institute of Systems, Molecular and Integrative Biology, University of Liverpool

Pat is Professor of Cell Signalling and Head of the Department of Biochemistry and Systems Biology, Institute of Systems, Molecular and Integrative Biology, where he runs a multidisciplinary research lab. He obtained an undergraduate degree in Biochemistry at the University of Bristol, and completed his PhD with Sir Philip Cohen at the University of Dundee in 2000. After 4 years of postdoctoral research in the USA with the late Jim Maller, he set up his laboratory in the UK with an MRC Career Development Fellowship in 2005. His interests include all aspects of protein phosphorylation and sulfation, analysis of protein kinase and sulfotransferase regulation, pseudokinases and pseudoenzymes and kinome-wide mechanisms of acquired drug resistance in cells. He also teaches cell signalling, running modules explaining the biochemical mechanisms underpinning cell communication.

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